Monday, June 4, 2007

Modeling of Arterial Cerebral Circulation

Studies of Cerebral aneurysm properties provide a better evaluation of their rupture’s danger, which may be deadly. As these properties change with time, ruptures are difficult to assess. CFD analysis is an efficient tool to provide information on the temporal variation of the mechanical forces acting on the aneurysm wall.

Intracranial arteries flow rate and pressure waveforms have to be provided as a boundary condition for CFD simulation in the vicinity of cerebral aneurysm. As the waveform changes from an artery to another, there’s a need to model main cerebral arteries to get the corresponding waveform. This model should go through a validation process to guatantee the result’s accuracy.

To improve and validate the model, reference results are needed: in vivo measurements to provide flow rate and pressure waveforms for cerebral modelled arteries. Measurements can be collected with MRI (general cerebral vasculature’s geometry), Doppler ultrasound (flow rate waveform) and Tonometry (pressure waveform) ,etc. The age range of study group is important. Young people’s artery properties is different from aged ones.


by: Virginie Chenaux

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